2nq3

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Template:STRUCTURE 2nq3

Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase

Template:ABSTRACT PUBMED 11318614

About this Structure

2nq3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chen X, Wen S, Fukuda MN, Gavva NR, Hsu D, Akama TO, Yang-Feng T, Shen CK. Human ITCH is a coregulator of the hematopoietic transcription factor NF-E2. Genomics. 2001 Apr 15;73(2):238-41. PMID:11318614 doi:10.1006/geno.2001.6512
  • Wood JD, Yuan J, Margolis RL, Colomer V, Duan K, Kushi J, Kaminsky Z, Kleiderlein JJ, Sharp AH, Ross CA. Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins. Mol Cell Neurosci. 1998 Jun;11(3):149-60. PMID:9647693 doi:10.1006/mcne.1998.0677
  • Winberg G, Matskova L, Chen F, Plant P, Rotin D, Gish G, Ingham R, Ernberg I, Pawson T. Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases. Mol Cell Biol. 2000 Nov;20(22):8526-35. PMID:11046148
  • Courbard JR, Fiore F, Adelaide J, Borg JP, Birnbaum D, Ollendorff V. Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH. J Biol Chem. 2002 Nov 22;277(47):45267-75. Epub 2002 Sep 10. PMID:12226085 doi:10.1074/jbc.M206460200

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