3ow4

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Image:3ow4.png

Template:STRUCTURE 3ow4

Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors

Template:ABSTRACT PUBMED 20971641

About this Structure

3OW4 is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bencsik JR, Xiao D, Blake JF, Kallan NC, Mitchell IS, Spencer KL, Xu R, Gloor SL, Martinson M, Risom T, Woessner RD, Dizon F, Wu WI, Vigers GP, Brandhuber BJ, Skelton NJ, Prior WW, Murray LJ. Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7037-41. Epub 2010 Sep 29. PMID:20971641 doi:10.1016/j.bmcl.2010.09.112

Page seeded by OCA on Wed Nov 24 12:39:23 2010

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