1m17

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Image:1m17.png

Template:STRUCTURE 1m17

Contents

Epidermal Growth Factor Receptor tyrosine kinase domain with 4-anilinoquinazoline inhibitor erlotinib

Template:ABSTRACT PUBMED 12196540

About this Structure

1m17 is a 1 chain structure with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.

See Also

Reference

  • Stamos J, Sliwkowski MX, Eigenbrot C. Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor. J Biol Chem. 2002 Nov 29;277(48):46265-72. Epub 2002 Aug 23. PMID:12196540 doi:10.1074/jbc.M207135200
  • Lawson CL, Benoff B, Berger T, Berman HM, Carey J. E. coli trp repressor forms a domain-swapped array in aqueous alcohol. Structure. 2004 Jun;12(6):1099-108. PMID:15274929 doi:10.1016/j.str.2004.03.019

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