2pzr

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Image:2pzr.png

Template:STRUCTURE 2pzr

Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome

Template:ABSTRACT PUBMED 17803937

About this Structure

2pzr is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chen H, Ma J, Li W, Eliseenkova AV, Xu C, Neubert TA, Miller WT, Mohammadi M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol Cell. 2007 Sep 7;27(5):717-30. PMID:17803937 doi:http://dx.doi.org/10.1016/j.molcel.2007.06.028

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