3up3

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Image:3up3.png

Template:STRUCTURE 3up3

Nuclear receptor DAF-12 from hookworm Ancylostoma ceylanicum in complex with (25S)-cholestenoic acid

Template:ABSTRACT PUBMED 22170062

About this Structure

3up3 is a 2 chain structure with sequence from Ancylostoma ceylanicum. Full crystallographic information is available from OCA.

Reference

  • Zhi X, Zhou XE, Melcher K, Motola DL, Gelmedin V, Hawdon J, Kliewer SA, Mangelsdorf DJ, Xu HE. Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes. J Biol Chem. 2011 Dec 21. PMID:22170062 doi:10.1074/jbc.M111.315242

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OCA

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