3tct

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Image:3tct.png

Template:STRUCTURE 3tct

Structure of wild-type TTR in complex with tafamidis

Template:ABSTRACT PUBMED 22645360

About this Structure

3tct is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bulawa CE, Connelly S, Devit M, Wang L, Weigel C, Fleming JA, Packman J, Powers ET, Wiseman RL, Foss TR, Wilson IA, Kelly JW, Labaudiniere R. Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9629-34. Epub 2012 May 29. PMID:22645360 doi:10.1073/pnas.1121005109

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