1ygc

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Image:1ygc.png

Template:STRUCTURE 1ygc

Contents

Short Factor VIIa with a small molecule inhibitor

Template:ABSTRACT PUBMED 15632123

About this Structure

1ygc is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Olivero AG, Eigenbrot C, Goldsmith R, Robarge K, Artis DR, Flygare J, Rawson T, Sutherlin DP, Kadkhodayan S, Beresini M, Elliott LO, DeGuzman GG, Banner DW, Ultsch M, Marzec U, Hanson SR, Refino C, Bunting S, Kirchhofer D. A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo. J Biol Chem. 2005 Mar 11;280(10):9160-9. Epub 2005 Jan 4. PMID:15632123 doi:10.1074/jbc.M409068200

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