3cjg
From Proteopedia
Contents |
Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine
Template:ABSTRACT PUBMED 18620382
About this Structure
3cjg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Harris PA, Boloor A, Cheung M, Kumar R, Crosby RM, Davis-Ward RG, Epperly AH, Hinkle KW, Hunter RN 3rd, Johnson JH, Knick VB, Laudeman CP, Luttrell DK, Mook RA, Nolte RT, Rudolph SK, Szewczyk JR, Truesdale AT, Veal JM, Wang L, Stafford JA. Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-m ethyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J Med Chem. 2008 Aug 14;51(15):4632-40. Epub 2008 Jul 12. PMID:18620382 doi:10.1021/jm800566m
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Nolte, R T. | Angiogenesis | Atp-binding | Developmental protein | Differentiation | Glycoprotein | Host-virus interaction | Immunoglobulin domain | Kinase insert domain receptor | Membrane | Nucleotide-binding | Phosphoprotein | Protein-tyrosine kinase receptor flk-1 | Transferase | Transmembrane | Tyrosine-protein kinase | Vascular endothelial growth factor receptor 2. vegfr-2
