3ri1
From Proteopedia
Crystal structure of the catalytic domain of FGFR2 kinase in complex with ARQ 069
Template:ABSTRACT PUBMED 21454610
About this Structure
3ri1 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Eathiraj S, Palma R, Hirschi M, Volckova E, Nakuci E, Castro J, Chen CR, Chan TC, France DS, Ashwell MA. A novel mode of protein kinase inhibition exploiting hydrophobic motifs of auto-inhibited kinases: discovery of ATP independent inhibitors of fibroblast growth factor receptor (FGFR). J Biol Chem. 2011 Mar 24. PMID:21454610 doi:10.1074/jbc.M110.213736
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Ashwell, M A. | Castro, J. | Chan, T C. | Chen, C R. | Eathiraj, S. | France, D S. | Hirschi, M. | Nakuci, E. | Palma, R. | Volckova, E. | Fgfr1 kinase | Fgfr2 kinase | Inactive conformation | Kinase-inhibitor complex | Transferase-transferase inhibitor complex
