4ere

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Template:STRUCTURE 4ere

crystal structure of MDM2 (17-111) in complex with compound 23

Template:ABSTRACT PUBMED 22524527

About this Structure

4ere is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rew Y, Sun D, Gonzalez-Lopez De Turiso F, Bartberger MD, Beck HP, Canon J, Chen A, Chow D, Deignan J, Fox BM, Gustin D, Huang X, Jiang M, Jiao X, Jin L, Kayser F, Kopecky DJ, Li Y, Lo MC, Long AM, Michelsen K, Oliner JD, Osgood T, Ragains M, Saiki AY, Schneider S, Toteva M, Yakowec P, Yan X, Ye Q, Yu D, Zhao X, Zhou J, Medina JC, Olson SH. Structure-Based Design of Novel Inhibitors of the MDM2-p53 Interaction. J Med Chem. 2012 May 9. PMID:22524527 doi:10.1021/jm300354j

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