3sqo
From Proteopedia
PCSK9 J16 Fab complex
Template:ABSTRACT PUBMED 22019884
About this Structure
3sqo is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liang H, Chaparro-Riggers J, Strop P, Geng T, Sutton JE, Tsai D, Bai L, Abdiche Y, Dilley J, Yu J, Wu S, Chin SM, Lee NA, Rossi A, Lin JC, Rajpal A, Pons J, Shelton DL. Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates. J Pharmacol Exp Ther. 2012 Feb;340(2):228-36. Epub 2011 Oct 21. PMID:22019884 doi:10.1124/jpet.111.187419
