3g1r

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Template:STRUCTURE 3g1r

Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A

Template:ABSTRACT PUBMED 19515843

About this Structure

3g1r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Drury JE, Di Costanzo L, Penning TM, Christianson DW. Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex. J Biol Chem. 2009 Jul 24;284(30):19786-90. Epub 2009 Jun 10. PMID:19515843 doi:10.1074/jbc.C109.016931

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Categories: Homo sapiens | Christianson, D W. | Costanzo, L Di. | Drury, J E. | Penning, T M. | Bile acid catabolism | Disease mutation | Finasteride complex | Intrahepatic cholestasis | Lipid metabolism | Nadp | Oxidoreductase | Steroid metabolism

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