3kpe

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Image:3kpe.png

Template:STRUCTURE 3kpe

Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with TMC353121, a small-moleucule inhibitor of RSV

Template:ABSTRACT PUBMED 19966279

About this Structure

3KPE is a 2 chains structure with sequences from Human respiratory syncytial virus a2. Full crystallographic information is available from OCA.

Reference

  • Roymans D, De Bondt HL, Arnoult E, Geluykens P, Gevers T, Van Ginderen M, Verheyen N, Kim H, Willebrords R, Bonfanti JF, Bruinzeel W, Cummings MD, van Vlijmen H, Andries K. Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein. Proc Natl Acad Sci U S A. 2009 Dec 4. PMID:19966279

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