3ld6
From Proteopedia
Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole
Template:ABSTRACT PUBMED 20149798
About this Structure
3LD6 is a 2 chains structure with sequences from Homo sapiens. This structure supersedes the now removed PDB entry 3i3k. Full crystallographic information is available from OCA.
Reference
- Strushkevich N, Usanov SA, Park HW. Structural basis of human CYP51 inhibition by antifungal azoles. J Mol Biol. 2010 Apr 9;397(4):1067-78. Epub 2010 Feb 10. PMID:20149798 doi:10.1016/j.jmb.2010.01.075
Page seeded by OCA on Thu May 20 08:58:41 2010
Categories: Homo sapiens | Sterol 14-demethylase | Arrowsmith, C H. | Bountra, C. | Edwards, A M | MacKenzie, F. | Park, H. | SGC, Structural Genomics Consortium. | Strushkevich, N. | Tempel, W. | Weigelt, J. | Alternative splicing | Cholesterol biosynthesis | Cytochrome p450 | Endoplasmic reticulum | Heme | Iron | Ketoconazole | Lipid synthesis | Membrane | Metal-binding | Microsome | Monooxygenase | Nadp | Oxidoreductase | Polymorphism | Sgc | Steroid biosynthesis | Sterol 14alpha-demethylase | Sterol biosynthesis | Structural genomic | Structural genomics consortium | Transmembrane
