3l1s

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Template:STRUCTURE 3l1s

3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3

Template:ABSTRACT PUBMED 20138514

About this Structure

3L1S is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Arnost M, Pierce A, ter Haar E, Lauffer D, Madden J, Tanner K, Green J. 3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1661-4. Epub 2010 Jan 21. PMID:20138514 doi:10.1016/j.bmcl.2010.01.072

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