3lpf

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Image:3lpf.jpg

Template:STRUCTURE 3lpf

Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea

Template:ABSTRACT PUBMED 21051639

About this Structure

3LPF is a 2 chains structure with sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Wallace BD, Wang H, Lane KT, Scott JE, Orans J, Koo JS, Venkatesh M, Jobin C, Yeh LA, Mani S, Redinbo MR. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science. 2010 Nov 5;330(6005):831-5. PMID:21051639 doi:10.1126/science.1191175

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