3mjr

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Image:3mjr.png

Template:STRUCTURE 3mjr

Human dCK complex with Acyclic Nucleoside

Template:ABSTRACT PUBMED 20684612

About this Structure

3MJR is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hazra S, Konrad M, Lavie A. The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic guanine analogues. J Med Chem. 2010 Aug 12;53(15):5792-800. PMID:20684612 doi:10.1021/jm1005379

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