3ms9

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Image:3ms9.png

Template:STRUCTURE 3ms9

ABL kinase in complex with imatinib and a fragment (FRAG1) in the myristate pocket

Template:ABSTRACT PUBMED 20450175

About this Structure

3MS9 is a 2 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Jahnke W, Grotzfeld RM, Pelle X, Strauss A, Fendrich G, Cowan-Jacob SW, Cotesta S, Fabbro D, Furet P, Mestan J, Marzinzik AL. Binding or bending: distinction of allosteric Abl kinase agonists from antagonists by an NMR-based conformational assay. J Am Chem Soc. 2010 May 26;132(20):7043-8. PMID:20450175 doi:10.1021/ja101837n

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