3njy

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Image:3njy.png

Template:STRUCTURE 3njy

Crystal structure of JMJD2A complexed with 5-carboxy-8-hydroxyquinoline

Template:ABSTRACT PUBMED 21124847

About this Structure

3NJY is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • King ON, Li XS, Sakurai M, Kawamura A, Rose NR, Ng SS, Quinn AM, Rai G, Mott BT, Beswick P, Klose RJ, Oppermann U, Jadhav A, Heightman TD, Maloney DJ, Schofield CJ, Simeonov A. Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. PLoS One. 2010 Nov 23;5(11):e15535. PMID:21124847 doi:10.1371/journal.pone.0015535

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