2fx3
From Proteopedia
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Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set
Overview
Escherichia coli elongation factor Tu-GDP (EF-Tu-GDP) was crystallized in, the presence of novel inhibitors. The only crystals which could be grown, were epitaxially as well as merohedrally twinned, highly mosaic and, diffracted to a resolution of 3.4 A in space group P3(1)21, with unit-cell, parameters a = b = 69.55, c = 169.44 A, alpha = beta = 90, gamma = 120, degrees . To determine whether an inhibitor was present in the crystal, a, poor-quality X-ray diffraction data set had to be processed. The, three-dimensional structure was ultimately solved and the original, question answered. The results also reveal a new type of dimer packing for, EF-Tu-GDP.
About this Structure
2FX3 is a Single protein structure of sequence from Escherichia coli with MG and GDP as ligands. Full crystallographic information is available from OCA.
Reference
Solving the structure of Escherichia coli elongation factor Tu using a twinned data set., Heffron SE, Moeller R, Jurnak F, Acta Crystallogr D Biol Crystallogr. 2006 Apr;62(Pt 4):433-8. Epub 2006, Mar 18. PMID:16552145
Page seeded by OCA on Wed Nov 21 10:49:13 2007
Categories: Escherichia coli | Single protein | Heffron, S.E. | Jurnak, F. | Moeller, R. | GDP | MG | Ef-tu | Merohedral twinning
