4iox

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Template:STRUCTURE 4iox

The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors

Template:ABSTRACT PUBMED 23596306

Function

[TRM3_HHV11] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation.

About this Structure

4iox is a 4 chain structure with sequence from Human herpesvirus 1. Full crystallographic information is available from OCA.

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