2yoa

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Template:STRUCTURE 2yoa

Synaptotagmin-1 C2B domain with phosphoserine

Function

[SYT1_RAT] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.

About this Structure

2yoa is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

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