4jr2
From Proteopedia
Human procaspase-7/caspase-7 heterodimer bound to Ac-DEVD-CMK
Function
[CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
About this Structure
4jr2 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
