Deaminase removes an amine group from a molecule. Cytosine deaminase (CDA) converts cytosine to uracil.
5-methylcytosine deaminase (MCDA) produces thymine. Guanine deaminase (GDA) converts guanine to xanthine. Adenine deaminase (ADA) converts adenine to hypoxanthine.
3D Structures of deaminase
Updated on 25-June-2013
Cytidine deaminase
1r5t – CDA - yeast
2a8n – AtCDA – Agrobacterium tumefaciens
2g84 – CDA – Nitrosomonas europaea
2d30 – CDA – Bacillus anthracis
3dmo – CDA – Burkholderia pseudomallei
3ijf – CDA – Mycobacterium tuberculosis
3mpz – CDA – Mycobacterium smegmatis
3r2n – CDA – Mycobacterium leprae
4f3w – CDA – Mycobacterium marinum
Cytidine deaminase complex with nucleoside
1ctt – EcCDA + dihydro-pyrimidinone – Escherichia coli
1ctu – EcCDA + hydroxyl-dihydro-zebularine
1af2 – EcCDA + uridine
1aln – EcCDA + deazacytidine
1jtk – BsCDA + tetrahydrodeoxyuridine - Bacillus subtilis
1uwz, 1ux0, 1ux1 – BsCDA (mutant) + tetrahydrodeoxyuridine
1mq0 – hCDA + β-ribofuranosyl diazepinone - human
1zab – mCDA + deazauridine - mouse
2fr5 – mCDA + tetrahydrouridine
2fr6 – mCDA + cytidine
4eg2 – CDA + uridine - Vibrio cholerae
Guanine deaminase
1tiy, 1wkq – BsGDA
Guanine deaminase complex with nucleoside
2i9u – GDA + guanine – Clostridium acetobutylicum
2ood – GDA + guanine – Bradrhizobium japonicum
2uz9 – hGDA + xanthine
4aql – hGDA + valacyclovir
Adenine deaminase
2ics – ADA - Enterococcus faecalis
3nqb, 3t81, 3t8l – AtADA
3ou8 – PaADA – Pseudomonas aeruginosa
Adenine deaminase complex with nucleoside
3pan – PaADA + hypoxanthine
3pao – PaADA + adenine
3pbm – PaADA + chloropurine
3rys – ADA + adenine – Arthrobacter aurescens
