1nth

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Template:STRUCTURE 1nth

Contents

Crystal structure of the methanosarcina barkeri monomethylamine methyltransferase (MTMB)

Template:ABSTRACT PUBMED 12029132

Function

[MTMB1_METBA] Catalyzes the transfer of the methyl group from monomethylamine to the corrinoid cofactor of MtmC (MtmC1 or MtmC2).[1] [2]

About this Structure

1nth is a 1 chain structure with sequence from Methanosarcina barkeri. This structure supersedes the now removed PDB entry 1l2r. Full crystallographic information is available from OCA.

Reference

  • Hao B, Gong W, Ferguson TK, James CM, Krzycki JA, Chan MK. A new UAG-encoded residue in the structure of a methanogen methyltransferase. Science. 2002 May 24;296(5572):1462-6. PMID:12029132 doi:10.1126/science.1069556
  1. Burke SA, Lo SL, Krzycki JA. Clustered genes encoding the methyltransferases of methanogenesis from monomethylamine. J Bacteriol. 1998 Jul;180(13):3432-40. PMID:9642198
  2. Burke SA, Krzycki JA. Reconstitution of Monomethylamine:Coenzyme M methyl transfer with a corrinoid protein and two methyltransferases purified from Methanosarcina barkeri. J Biol Chem. 1997 Jun 27;272(26):16570-7. PMID:9195968

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