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2j9a
From Proteopedia
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BLLAP IN COMPLEX WITH MICROGININ FR1
Overview
Natural bioactive compounds are of general interest for pharmaceutical, research because they may serve as leads in drug development campaigns., Among them, microginins are linear peptides known to inhibit various, exopeptidases. The crystal structure of microginin FR1 from Microcystis, sp. bound to bovine lens leucine aminopeptidase was established at 1.73, Angstrom resolution. The observed binding structure could be beneficial, for the design of potent aminopeptidase inhibitors.
About this Structure
2J9A is a Single protein structure of sequence from Bos taurus and Microcystis sp. with , , , and as ligands. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Binding structure of the leucine aminopeptidase inhibitor microginin FR1., Kraft M, Schleberger C, Weckesser J, Schulz GE, FEBS Lett. 2006 Dec 22;580(30):6943-7. Epub 2006 Dec 4. PMID:17157838
Page seeded by OCA on Sun Feb 3 10:43:05 2008
Categories: Bos taurus | Microcystis sp. | Single protein | Kraft, M. | Schleberger, C. | Schulz, G.E. | Weckesser, J. | AHY | CL | DMS | MPD | ZN | Acetylation | Aminopeptidase | Inhibitor complex hydrolase | Leucine aminopeptidase | Metal-binding | Microcystins | Microginin | Protease
