4fhb

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Template:STRUCTURE 4fhb

Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)

Function

[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

4fhb is a 2 chain structure with sequence from Escherichia coli k-12 and Lama glama. Full crystallographic information is available from OCA.

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