4mqs
From Proteopedia
Contents |
Structure of active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo
Disease
[ACM2_HUMAN] Disease susceptibility is associated with variations affecting the gene represented in this entry.
Function
[ACM2_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.
About this Structure
4mqs is a 2 chain structure. Full crystallographic information is available from OCA.
Categories: Christopoulos, A. | Eitel, K. | Felder, C C. | Garcia, K C. | Gmeiner, P. | Hu, J. | Hu, K. | Huebner, H. | Kobilka, B K. | Kruse, A C. | Manglik, A. | Pardon, E. | Ring, A M. | Sexton, P M. | Steyaert, J. | Valant, C. | Weis, W I. | Wess, J. | G protein-coupled receptor | Muscarinic acetylcholine receptor | Signaling protein
