2bem
From Proteopedia
|
CRYSTAL STRUCTURE OF THE SERRATIA MARCESCENS CHITIN-BINDING PROTEIN CBP21
Overview
Chitin proteins are commonly found in bacteria that utilize chitin as a, source of energy. CBP21 is a chitin-binding protein from Serratia, marcescens, a Gram-negative soil bacterium capable of efficient chitin, degradation. When grown on chitin, S. marcescens secretes large amounts of, CBP21, along with chitin-degrading enzymes. In an attempt to understand, the molecular mechanism of CBP21 action, we have determined its crystal, structure at 1.55 angstroms resolution. This is the first structure to be, solved of a family 33 carbohydrate-binding module. The structure reveals a, "budded" fibronectin type III fold consisting of two beta-sheets, arranged, as a beta-sheet sandwich, with a 65-residue "bud" consisting of three, short helices, located between beta-strands 1 and 2. Remarkably, ... [(full description)]
About this Structure
2BEM is a [Single protein] structure of sequence from [Serratia marcescens] with SO4, NA and EDO as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure and binding properties of the Serratia marcescens chitin-binding protein CBP21., Vaaje-Kolstad G, Houston DR, Riemen AH, Eijsink VG, van Aalten DM, J Biol Chem. 2005 Mar 25;280(12):11313-9. Epub 2004 Dec 8. PMID:15590674
Page seeded by OCA on Tue Oct 30 13:41:45 2007
