User:Chengfeng Ren/IFN beta 1a

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Contents 1 IFN Categories and IFNβ-1a sources 2 Structure info. of IFNβ-1a 3 IFNβ-1a biological activity and therapeutic effects 4 Mechanism of action for IFNβ-1a 5 Reference

IFN Categories and IFNβ-1a sources

Interferons (IFNs) are a family of helical cytokines that mediate antiviral, antiproliferative, and immune modulatory activities in response to biological and chemical stimuli. Two types of IFN are recognized on the basis of their physical and biological properties; type I, which contains the monomeric IFNs-α,-β,-τ, and -ω, and type II, the only member of which is the dimeric IFN-γ. Representatives of all type I and type II IFNs are found in humans, except for IFN-τ, which is found only in ruminant ungulates. There are 12 different human IFNs-α;each one comprising a different subtype,although 14 different genes have been identified, whereas human IFN-β, IFN-ω, and IFN-γare encoded by single genes.

Structure info. of IFNβ-1a

IFNβ-1a biological activity and therapeutic effects

Mechanism of action for IFNβ-1a

Reference

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