2tmk

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Image:2tmk.jpg

2tmk, resolution 2.4Å

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YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)

About this Structure

2TMK is a Single protein structure of sequence from Saccharomyces cerevisiae with SO4 and ATM as ligands. Active as dTMP kinase, with EC number 2.7.4.9 Full crystallographic information is available from OCA.

Reference

Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation., Lavie A, Vetter IR, Konrad M, Goody RS, Reinstein J, Schlichting I, Nat Struct Biol. 1997 Aug;4(8):601-4. PMID:9253404

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