4bw9

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Template:STRUCTURE 4bw9

Contents

PylRS Y306G, Y384F, I405R mutant in complex with AMP-PNP

Template:ABSTRACT PUBMED 24027216

Function

[PYLS_METMA] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).

About this Structure

4bw9 is a 1 chain structure with sequence from Methanosarcina mazei. Full crystallographic information is available from OCA.

Reference

  • Schneider S, Gattner MJ, Vrabel M, Flugel V, Lopez-Carrillo V, Prill S, Carell T. Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins. Chembiochem. 2013 Sep 11. doi: 10.1002/cbic.201300435. PMID:24027216 doi:10.1002/cbic.201300435

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