Sandbox Reserved 816

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Revision as of 17:48, 7 January 2014 by Lecomte Alix (Talk | contribs)
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This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543.
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Introduction

Internalin K is a protein from Listeria monocytogene , which is a Gram-positive bacterium human pathogen. Its ability to survive in the human intestine and to cross a variety of membranes, including mucosal, intestinal, placental, and blood–brain barriers, allows it to generate illnesses ranging from gastroenteritis in healthy individuals to bacteremia and meningitis in immunocompromised patients, as well as mother-to-child infections. Listeria monocytogene can survive in a variety of cell types and proteins of the internalin family have been shown to play a key role in this survival.

Internalin K is involved in Listeria monocytogene ability to escape from autophagy by recruitment of major vault protein to the bacterial surface.




major vault protein

Listeria monocytogene

Gram-positive bacterium


Image:Chain1.png


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