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3m7o

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Template:STRUCTURE 3m7o

Contents

Crystal structure of mouse MD-1 in complex with phosphatidylcholine

Template:ABSTRACT PUBMED 020595044

Function

[LY86_MOUSE] May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.[1]

About this Structure

3m7o is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. ↑ Gorczynski RM, Chen Z, Clark DA, Hu J, Yu G, Li X, Tsang W, Hadidi S. Regulation of gene expression of murine MD-1 regulates subsequent T cell activation and cytokine production. J Immunol. 2000 Aug 15;165(4):1925-32. PMID:10925274

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