4dx5

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Template:STRUCTURE 4dx5

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

Template:ABSTRACT PUBMED 22451937

About this Structure

4dx5 is a 5 chain structure with sequence from Escherichia coli and Synthetic construct. Full crystallographic information is available from OCA.

Reference

  • Eicher T, Cha HJ, Seeger MA, Brandstatter L, El-Delik J, Bohnert JA, Kern WV, Verrey F, Grutter MG, Diederichs K, Pos KM. Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5687-92. Epub 2012 Mar 26. PMID:22451937 doi:10.1073/pnas.1114944109

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