3zif

From Proteopedia

Revision as of 07:00, 22 January 2014 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 3zif

Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly

Function

[CAPSH_ADEB3] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus (By similarity).

About this Structure

3zif is a 18 chain structure with sequence from Bovine adenovirus 3. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools