1b4q

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Template:STRUCTURE 1b4q

Solution structure of human thioltransferase complex with glutathione

Template:ABSTRACT PUBMED 9860827

About this Structure

1b4q is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Yang Y, Jao S, Nanduri S, Starke DW, Mieyal JJ, Qin J. Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity. Biochemistry. 1998 Dec 8;37(49):17145-56. PMID:9860827 doi:10.1021/bi9806504
  • Jao SC, English Ospina SM, Berdis AJ, Starke DW, Post CB, Mieyal JJ. Computational and mutational analysis of human glutaredoxin (thioltransferase): probing the molecular basis of the low pKa of cysteine 22 and its role in catalysis. Biochemistry. 2006 Apr 18;45(15):4785-96. PMID:16605247 doi:10.1021/bi0516327

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