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1e92

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Image:1e92.png

Template:STRUCTURE 1e92

PTERIDINE REDUCTASE 1 FROM LEISHMANIA MAJOR COMPLEXED WITH NADP+ AND DIHYDROBIOPTERIN

Template:ABSTRACT PUBMED 11373620

About this Structure

1e92 is a 4 chain structure with sequence from Leishmania major. Full crystallographic information is available from OCA.

Reference

  • Gourley DG, Schuttelkopf AW, Leonard GA, Luba J, Hardy LW, Beverley SM, Hunter WN. Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites. Nat Struct Biol. 2001 Jun;8(6):521-5. PMID:11373620 doi:10.1038/88584
  • Zhao H, Bray T, Ouellette M, Zhao M, Ferre RA, Matthews D, Whiteley JM, Varughese KI. Structure of pteridine reductase (PTR1) from Leishmania tarentolae. Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1539-44. Epub 2003, Aug 19. PMID:12925782

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OCA

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