1u9q

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Image:1u9q.png

Template:STRUCTURE 1u9q

Crystal structure of cruzain bound to an alpha-ketoester

Template:ABSTRACT PUBMED 15727867

About this Structure

1u9q is a 1 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

Reference

  • Choe Y, Brinen LS, Price MS, Engel JC, Lange M, Grisostomi C, Weston SG, Pallai PV, Cheng H, Hardy LW, Hartsough DS, McMakin M, Tilton RF, Baldino CM, Craik CS. Development of alpha-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease. Bioorg Med Chem. 2005 Mar 15;13(6):2141-56. PMID:15727867 doi:10.1016/j.bmc.2004.12.053

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