Ribosomal protein L14

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Image:1whi.png
Crystal Structure of Ribosomal protein L14 (1whi)

Template:STRUCTURE 1whi

Ribosomal protein L14 (RPL14) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. The images at the left and at the right correspond to one representative RPL14, i.e. the crystal structure of Ribosomal protein L14 from Geobacillus stearothermophilus (1whi).







3D Structures of Ribosomal protein L14

Updated on 12-November-2013

RPL14

2kds, 2joy – RPL14 – Sulfolobus solfataricus – NMR
1whi – RPL14 – Geobacillus stearothermophilus

L14 in 50S subunit+RNA

2xg0, 2xg2, 3kir, 3kit, 3kiw, 3kiy, 4byc, 4bye – TtRPL14 in 50S subunit+RNA fragments - Thermus thermophilus
2x9s, 2x9u, 3kni, 3knk, 3knm, 3kno, 2wrj, 2wrl, 2wro, 2wrr, 3hux, 3huz, 2wh2, 2wh4, 2wdi, 2wdj, 2wdl, 2wdn, 1vsp, 2v47, 2v49, 1vsa, 2hgj, 2hgq, 2hgu, 2j01, 2j03, 1yl3, 3mrz, 3ms1, 3i8f, 3i8i, 3i9c, 3i9e, 3f1f, 3f1h, 3d5b, 3d5d, 2b66, 2b9n, 2b9p, 1giy, 2xqe, 4btd, 4kfi, 4kfl, 4kbu, 4kbw, 4kcz, 4kd2, 4kd9, 4kdb, 4kdh, 4kdk, 4k0m, 4k0q, 4jux, 4ejb, 4ejc, 3v6x, 3v6w, 4b8g, 4b8i, 3zn9, 3zne, 4g5l, 4g5n, 4g5u, 4g5w, 3v23, 3v25, 3v27, 3v29, 3v2d, 3v2f, 4dha, 4dhc, 4abs, 3uz1, 3uz2, 3uz8, 3uz9, 3uzf, 3uzh, 3uzk, 3uzn, 3uye, 3uyg, 3tve, 3tvh, 3uxq, 3uxr, 3zvp, 2y0v, 2y0x, 2y0z, 2y11, 2y13, 2y15, 2y17, 2y19, 3pyo, 3pyr, 3pyt, 3pyv, 3oh5, 3oh7, 3ohj, 3ohk , 3ohz, 3oi1, 3oi3, 3oi5 - TtRPL14 in 50S subunit+5S RRNA+23S RRNA
3fin, 2xtg, 2xux - TtRPL14 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM
2wwq – EcRPL14 in 50S subunit+5S RRNA+23S RRNA+mRNA+P-site tRNA – Escherichia coli
3i1n, 3i1p, 3i1r, 3i1t, 3i20, 3i22, 3e1b, 3e1d, 3df2, 3df4, 2vhn, 2qov, 2qox, 2i2t, 2i2v, 1vs6, 1vs8, 2aw4, 2awb, 1vor, 1vou, 1vow, 1voy, 1vp0, 1pnu, 1pny, 4kix, 4kiz, 4kj1, 4kj3, 4kj5, 4kj7, 4kj9, 4kjb , 3uos, 3sgf, 3r8s, 3r8t, 3oas, 3oat - EcRPL14 in 50S subunit+5S RRNA+23S RRNA
3fik, 2gya, 2gyc, 3bbx, 1p85, 1p86, 3j0t, 3j0w, 3j0y, 3j11, 3j12, 3j14, 3j19, 3izu, 3izt - EcRPL14 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM
3bbo - RPL13 in 50S subunit+5S RRNA+23S RRNA+4.8S RRNA – Cryo-EM – spinach
2zjq, 2zjr, 1nkw, 3pio, 3pip - DrRPL14 in 50S subunit+5S RRNA+23S RRNA – Deinococcus radiodurans
1kqs, 1qvg - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+CCA - Haloarcula marismortui
1jj2, 1ffk, 3cc2, 2qa4, 1s72 - HmRPL14P in 50S subunit+5S RRNA+23S RRNA
3cc7, 3cce, 3ccj, 3ccl, 3ccm, 3ccq, 3ccr, 3ccs, 3ccu, 3ccv - HmRPL14P in 50S subunit+5S RRNA+23S RRNA (mutant)
1yj9 - HmRPL14P in 50S subunit (L22 mutant)+5S RRNA+23S RRNA
1vq4, 1vq5, 1vq7, 1vql, 1vqm, 1vqp - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+transition state analog
1vq6, 1vqk, 1vqn - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+ c-hpmn+CCA-Phe-caproic acid-biotin
1q86 - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+CCA-Phe-caproic acid-biotin
1vqo - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+ CCPMN
1qvf - HmRPL14P in 50S subunit+5S RRNA+23S RRNA + deacylated tRNA minihelix
3iy9 – RPL14 in 50S subunit – Leishmania taretolae
3j3v, 3j3w - RPL14 in 50S subunit+5S RRNA+23S RRNA – Bacillus subtilis

L14 in 50S subunit + antibiotics

3cxc – RPL14 in 50S subunit+5S RRNA+23S RRNA +oxazolidinone inhibitor – Halobacterium marismortui
3dll - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+oxazolidinone inhibitor
2zjp - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+nosiheptide
3cf5 - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+thiostrepton
1xbp - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+thiamulin
1sm1 - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+quinupristin+dalfopristin
1nwx - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+ABT-773
4io9, 4ioa, 4ioc, 1nwy - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+ antibiotics
2qam, 2qao, 2qoz, 2qp1, 2qba, 2qbc, 4gar, 4gau - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+antibiotics
1k73, 1kc8, 1k8a, 1k9m, 1kd1, 1m1k, 3i55, 3i56, 3g4s, 3g6e, 3g71, 2qex, 3cc4, 3cd6, 2otj, 2otl, 1yit, 1q7y, 1q81, 1q82, 1n8r, 1nji - HmRPL13P in 50S subunit+5S RRNA+23S RRNA+antibiotic
1yhq, 1yi2, 1yij, 1yjn, 1yjw - HmRPL14P in 50S subunit+5S RRNA+23S RRNA (mutant)+antibiotic
1m90, 3cma, 3cme, 1vq8, 1vq9 - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+ sparsomycin+CCA-Phe-caproic acid-biotin
4l6l, 4l6j - TtRPL14 in 50S subunit+5S RRNA+23S RRNA + antibiotics

L14 in large + small ribosomal subunit

1ml5 - EcRPL14 in 50S ribosomal subunit+30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA – EM

L14 in 50S subunit + ribosome releasing factor (RRF)

2qbe, 2qbg, 2qbi, 2qbk, 2z4l, 2z4n - EcRPL13 in 50S subunit+5S RRNA+23S RRNA+RRF
2rdo - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+EF-G+RRF – Cryo-EM

L14 in 50S subunit + various proteins

2vhm - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+PDF C-terminal helix
2j28 - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+signal recognition particle – Cryo-EM
3j01, 3kcr - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+ preprotein translocase
1w2b - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+trigger factor N-terminal

L14 in part of 50S subunit

1c04 – HmRPL14P+RPL2+RPL6+RPL11+23S RRNA fragment
487d – RPL14+RPL1+RPL2+RPL9+RPL11+RPL6+RPL25 – Cryo-EM

L14 in 60S subunit

4a18, 4a19, 4a1b, 4a1d - RPL14 in 60S ribosomal subunit+ 26S RRNA+ translation initiation factor 6 – Tetrahymena thermophila
3j39 - RPL14 in 60S ribosomal subunit – Drosophila melanogaster – Cryo-EM
3j3b - RPL14 in 60S ribosomal subunit – human – Cryo-EM

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Alexander Berchansky, Michal Harel, Joel L. Sussman

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