4m90

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Template:STRUCTURE 4m90

Contents 1 crystal structure of oxidized hN33/Tusc3 2 Disease 3 Function 4 About this Structure 5 Reference

crystal structure of oxidized hN33/Tusc3

Disease

[TUSC3_HUMAN] Autosomal recessive nonsyndromic intellectual deficit. The disease is caused by mutations affecting the gene represented in this entry.

Function

[TUSC3_HUMAN] Magnesium transporter. May be involved in N-glycosylation through its association with N-oligosaccharyl transferase.^[1]

About this Structure

4m90 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

1. ↑ Zhou H, Clapham DE. Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15750-5. Epub 2009 Aug 26. PMID:19717468 doi:http://dx.doi.org/0908332106