4cjm
From Proteopedia
Contents |
Crystal structure of human FGF18
Function
[FGF18_HUMAN] Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.[1]
About this Structure
4cjm is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Brown A, Adam LE, Blundell TL. The crystal structure of fibroblast growth factor 18 (FGF18). Protein Cell. 2014 Mar 26. PMID:24668462 doi:http://dx.doi.org/10.1007/s13238-014-0033-4
- ↑ Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem. 2006 Jun 9;281(23):15694-700. Epub 2006 Apr 4. PMID:16597617 doi:10.1074/jbc.M601252200