4ip9

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Template:STRUCTURE 4ip9

Contents

Structure of native human serum amyloid A1

Disease

[SAA1_HUMAN] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer.

Function

[SAA1_HUMAN] Major acute phase reactant. Apolipoprotein of the HDL complex.

About this Structure

4ip9 is a 2 chain structure. Full crystallographic information is available from OCA.

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