2mmz

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Template:STRUCTURE 2mmz

Contents

Solution structure of the apo form of human glutaredoxin 5

Disease

[GLRX5_HUMAN] Adult-onset autosomal recessive sideroblastic anemia. The disease is caused by mutations affecting the gene represented in this entry.

Function

[GLRX5_HUMAN] Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.

About this Structure

2mmz is a 1 chain structure. Full experimental information is available from OCA.

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