3epx

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Image:3epx.png

Template:STRUCTURE 3epx

Crystal structure of Trypanosoma vivax nucleoside hydrolase in complex with the inhibitor (2R,3R,4S)-2-(hydroxymethyl)-1-(quinolin-8-ylmethyl)pyrrolidin-3,4-diol

Template:ABSTRACT PUBMED 19281874

About this Structure

3epx is a 2 chain structure with sequence from Trypanosoma vivax. Full crystallographic information is available from OCA.

Reference

  • Versees W, Goeminne A, Berg M, Vandemeulebroucke A, Haemers A, Augustyns K, Steyaert J. Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors. Biochim Biophys Acta. 2009 Jun;1794(6):953-60. Epub 2009 Mar 10. PMID:19281874 doi:10.1016/j.bbapap.2009.02.011

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