3h5z

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Template:STRUCTURE 3h5z

Crystal Structure of Leishmania major N-myristoyltransferase with bound myristoyl-CoA

Template:ABSTRACT PUBMED 20360736

About this Structure

3h5z is a 1 chain structure with sequence from Leishmania major. Full crystallographic information is available from OCA.

Reference

  • Frearson JA, Brand S, McElroy SP, Cleghorn LA, Smid O, Stojanovski L, Price HP, Guther ML, Torrie LS, Robinson DA, Hallyburton I, Mpamhanga CP, Brannigan JA, Wilkinson AJ, Hodgkinson M, Hui R, Qiu W, Raimi OG, van Aalten DM, Brenk R, Gilbert IH, Read KD, Fairlamb AH, Ferguson MA, Smith DF, Wyatt PG. N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Nature. 2010 Apr 1;464(7289):728-32. PMID:20360736 doi:10.1038/nature08893

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