1af9

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Image:1af9.jpg

1af9, resolution 2.7Å

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TETANUS NEUROTOXIN C FRAGMENT

Overview

The 2.7 A structure of the tetanus neurotoxin receptor binding fragment Hc reveals a jelly-roll domain and a beta-trefoil domain. Hc retains the unique transport properties of the holotoxin and is capable of eliciting a protective immunological response against the full length holotoxin.

About this Structure

1AF9 is a Single protein structure of sequence from Clostridium tetani. Active as Tentoxilysin, with EC number 3.4.24.68 Full crystallographic information is available from OCA.

Reference

Structure of the receptor binding fragment HC of tetanus neurotoxin., Umland TC, Wingert LM, Swaminathan S, Furey WF, Schmidt JJ, Sax M, Nat Struct Biol. 1997 Oct;4(10):788-92. PMID:9334741

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