3qe0
From Proteopedia
A Galpha-i1 P-loop mutation prevents transition to the activated state
Template:ABSTRACT PUBMED 22383884
About this Structure
3qe0 is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bosch DE, Willard FS, Ramanujam R, Kimple AJ, Willard MD, Naqvi NI, Siderovski DP. A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis. PLoS Pathog. 2012 Feb;8(2):e1002553. Epub 2012 Feb 23. PMID:22383884 doi:10.1371/journal.ppat.1002553
- Johnston CA, Willard FS, Jezyk MR, Fredericks Z, Bodor ET, Jones MB, Blaesius R, Watts VJ, Harden TK, Sondek J, Ramer JK, Siderovski DP. Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange. Structure. 2005 Jul;13(7):1069-80. PMID:16004878 doi:10.1016/j.str.2005.04.007
Categories: Heterotrimeric G-protein GTPase | Homo sapiens | Bosch, D E. | Kimple, A J. | Miley, M J. | Siderovski, D P. | Willard, F S. | Adp-ribosylation | All-helical domain | Arginine finger | Gtp binding | Gtpase activity | Kb752 | Lipoprotein | Nucleotide binding | Ras-like domain | Signaling protein | Transducer
