3qd4
From Proteopedia
Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}carbamate
Template:ABSTRACT PUBMED 21341675
About this Structure
3qd4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Medina JR, Becker CJ, Blackledge CW, Duquenne C, Feng Y, Grant SW, Heerding D, Li WH, Miller WH, Romeril SP, Scherzer D, Shu A, Bobko MA, Chadderton AR, Dumble M, Gardiner CM, Gilbert S, Liu Q, Rabindran SK, Sudakin V, Xiang H, Brady PG, Campobasso N, Ward P, Axten JM. Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors. J Med Chem. 2011 Feb 22. PMID:21341675 doi:10.1021/jm101527u
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Axten, J M. | Becker, C J. | Blackledge, C W. | Bobko, M A. | Brady, P G. | Campobasso, N. | Chadderton, A R. | Dumble, M. | Duquenne, C. | Feng, Y. | Gilbert, S. | Gradiner, C M. | Grant, S W. | Heerding, D. | Li, W H. | Liu, Q. | Medina, J R. | Miller, W H. | Rabindran, S K. | Romeril, S P. | Scherzer, D. | Shu, A. | Sudakin, V. | Ward, P. | Xiang, H. | Agc kinase | Atp & phosphoinositide | Kinase domain | Phosphorylation on s241 | Signal tranduction | Transferase-transferase inhibitor complex
