3p9j

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Image:3p9j.png

Template:STRUCTURE 3p9j

Aurora A kinase domain with phthalazinone pyrazole inhibitor

Template:ABSTRACT PUBMED 21128645

About this Structure

3p9j is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Prime ME, Courtney SM, Brookfield FA, Marston RW, Walker V, Warne J, Boyd AE, Kairies NA, von der Saal W, Limberg A, Georges G, Engh RA, Goller B, Rueger P, Rueth M. Phthalazinone Pyrazoles as Potent, Selective, and Orally Bioavailable Inhibitors of Aurora-A Kinase. J Med Chem. 2010 Dec 3. PMID:21128645 doi:10.1021/jm101346r

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